−30%
99.52% purityOriginal COAResearch Use Only
Compound · Tissue Repair
KPV
Research compound · Research Use Only
KPV — research compound supplied by Purple Peptides with batch-level documentation. For laboratory research use only.
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$43.99$30.79
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Tissue Repair research compounds
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Available original certificates give you a clear record you can open before you order. Research transparency is the standard — not an add-on.
- Batch-level documentation
- Purity verified by HPLC
- Research Use Only supply
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Every vial earns its release through documented proof, not marketing language. Review the supplied certificate for the selected strength. Results apply only to its tested samples; unavailable documentation is marked pending.
PV
Freedom Diagnostics
Reported October 3, 2026 · 10mg
Certificate of Analysis
99.52%
Purity by HPLC
- Tested
- October 3, 2026
- Labeled
- 10mg
- Measured
- 11.75 mg
Original certificateReported results
Batch testing
Purity
HPLC-UV · analytical result
99.52%REPORTED
Sample 1 purity
HPLC-UV · sample summary
99.51%REPORTED
Sample 2 purity
HPLC-UV · sample summary
99.52%REPORTED
Identity
LC-MS
KPVREPORTED
Net content
Reported analytical result
11.75 mgREPORTED
Appearance
Sample summary
White Lyophilized PowderREPORTED
Elemental impurities
ICP-MS · As / Cd / Pb / Hg
Below reporting/specification limits✓ PASS
Microbial analysis
PCR
No Detectable Microbial DNAREPORTED
Endotoxin
USP <85> · LAL
Replicates 1 and 2: Pass · sensitivity ≤0.05 EU/mL✓ PASS
Fentanyl screen
Sample summary
No Fentanyl DetectedREPORTED
Results are transcribed from the supplied original. A reported purity value is not a pass/fail claim. Missing tests are not inferred.
Certificates of Analysis · latest batches
KPV 10mg
99.52% purity (HPLC)
What the standard requires
01
Reported Purity
Exact HPLC-UV results from supplied samples.
02
Double Tested
Manufacturer + independent third-party.
03
Batch Traceable
Chain-of-custody documented end to end.
04
Purple Verified™
Released only after alignment.
Technical specifications
Compound Information
Molecular profile
What Is KPV?
- Category
- Tissue Repair
- Also known as
- Lys-Pro-Val · α-MSH (11–13)
- Classification
- Synthetic tripeptide · 3 amino acids
- Sequence
- Lys-Pro-Val (KPV)
- Molecular Formula
- C₁₆H₃₀N₄O₄
- Molecular Weight
- 342.43 g/mol
- Form
- Sealed research vial
Storage requirements
Stability Information
Lyophilized (sealed vial)
Storage information pending final content approval.
2–8°C
Reconstituted
Keep refrigerated at 2–8°C after reconstitution.
Reconstituted vials are stored refrigerated at 2–8°C. Remaining Purple-approved storage guidance will appear here once confirmed.
Research overview · preclinical evidence
What the published research investigates.
What is KPV?
KPV is a tripeptide (lysine–proline–valine) that corresponds to the C-terminal amino acids 11–13 of alpha-melanocyte-stimulating hormone (α-MSH). The literature studies it as a small fragment that may retain some of α-MSH's anti-inflammatory activity observed in experimental models (Brzoska et al., 2008). Published work on KPV is in vitro and preclinical.
Research areas investigated
Intestinal inflammation models: cell and mouse studies examined KPV uptake through the PepT1 peptide transporter and reduced inflammatory signaling (Dalmasso et al., 2008), and its effects in murine colitis models (Kannengiesser et al., 2008). Delivery research: oral nanoparticle formulations were tested in mouse colitis models (Xiao et al., 2017). Researchers in tissue biology also study BPC-157 and TB-500.
Mechanisms studied
Proposed mechanisms in these models include transport into intestinal epithelial cells via PepT1 and reduced NF-κB and MAP-kinase inflammatory signaling. These observations come from specific experimental systems and are not established in humans.
Limitations of the evidence
No controlled human clinical trials of KPV are reported in the references below. Findings come from cell culture and rodent models and do not establish effects, safety or efficacy in humans. Explore more at the Research Institute.
Peer-reviewed literature
The research behind this compound, cited in full.
Research context on this page traces back to the 4 publications below.
- 01Endocrine Reviews · 2008α-Melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseasesBrzoska T, Luger TA, Maaser C, et al.Review of α-MSH and its C-terminal tripeptides, including KPV, across experimental models.
- 02Gastroenterology · 2008PepT1-mediated tripeptide KPV uptake reduces intestinal inflammationDalmasso G, Charrier-Hisamuddin L, Nguyen HTT, et al.In vitro and preclinical (intestinal cells and mice): KPV entered cells via PepT1 and was associated with reduced inflammatory signaling.
- 03Inflammatory Bowel Diseases · 2008Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel diseaseKannengiesser K, Maaser C, Heidemann J, et al.Preclinical (mouse colitis models): KPV was associated with reduced markers of intestinal inflammation.
- 04Molecular Therapy · 2017Orally targeted delivery of tripeptide KPV via hyaluronic acid-functionalized nanoparticles efficiently alleviates ulcerative colitisXiao B, Xu Z, Viennois E, et al.Preclinical (mice): a nanoparticle delivery approach for KPV was evaluated in colitis models.
Research FAQs
Frequently asked questions.
What is KPV?
KPV is a synthetic tripeptide (lysine–proline–valine) matching the C-terminal residues 11–13 of α-MSH. Purple Peptides supplies it for laboratory research use only.
What does the scientific literature investigate about KPV?
Published studies examine KPV in cell and mouse models of intestinal inflammation, its uptake through the PepT1 transporter, and oral delivery formulations. See the references on this page.
Is there human clinical evidence for KPV?
The references on this page are cell and animal studies. No controlled human clinical trials are cited, so findings should not be read as evidence of effects in humans.
How is KPV related to α-MSH?
α-MSH is a 13-amino-acid peptide. KPV corresponds to its last three amino acids and is studied as a small fragment of the parent hormone (Brzoska et al., 2008).
What is the difference between peptide identity and purity?
Identity confirms the material is the intended molecule, typically by mass spectrometry. Purity measures how much of the sample is that molecule relative to other detected components, typically by HPLC.
What does Research Use Only mean?
The product is sold exclusively for laboratory research. It is not for human or veterinary use and is not intended to diagnose, treat, cure or prevent any disease. Learn about our testing approach on The Purple Standard™ or browse All Products.
Important research notice
Not for human, veterinary, or food use. This product is sold exclusively for laboratory research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
Published research referenced on this page is provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.
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